Fixtures & Results
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| Sunday, 05/09/2021 - Senior F Preliminary |
| Tyldesley Senior U18 Colts | 19 | 5 | Kendal Senior U18 Colts |
| Sunday, 12/09/2021 - Senior F Preliminary |
| Tyldesley Senior U18 Colts | v | Transition Week |
| Sunday, 19/09/2021 - Senior F Preliminary |
| Widnes Senior U18 Colts | 12 | 42 | Tyldesley Senior U18 Colts |
| Sunday, 26/09/2021 - Lancashire Colts: Frank Morgan U18 Cup |
| Preston Grasshoppers Senior U18 Colts | 27 | 20 | Tyldesley Senior U18 Colts |
| Sunday, 03/10/2021 - Senior F Preliminary |
| Tyldesley Senior U18 Colts | Away Walkover | Aldwinians Senior U18 Colts |
| Sunday, 17/10/2021 - Senior F Preliminary |
| Glossop Senior U18 Colts | v | Tyldesley Senior U18 Colts |
| Sunday, 24/10/2021 - Lancashire Colts: Joe McDonough U18 Trophy |
| Tyldesley Senior U18 Colts | v | Bye |
| Sunday, 14/11/2021 - Senior G Conference |
| Tyldesley Senior U18 Colts | Liquidated Fixture | Bury Senior U18 Colts |
| Sunday, 21/11/2021 - Senior G Conference |
| Bolton Senior U18 Colts | 10 | 22 | Tyldesley Senior U18 Colts |
| Sunday, 28/11/2021 - Senior G Conference |
| Tyldesley Senior U18 Colts | v | Recovery Week |
| Sunday, 12/12/2021 - Senior G Conference |
| Tyldesley Senior U18 Colts | 56 | 5 | Widnes Senior U18 Colts |
| Sunday, 23/01/2022 - Senior G Conference |
| Blackburn Senior U18 Colts | 48 | 0 | Tyldesley Senior U18 Colts |
| Sunday, 30/01/2022 - Senior G Conference |
| Tyldesley Senior U18 Colts | 41 | 28 | Bolton Senior U18 Colts |
| Sunday, 13/02/2022 - Senior G Conference |
| Recovery Week | v | Tyldesley Senior U18 Colts |
| Sunday, 20/02/2022 - Senior G Conference |
| Widnes Senior U18 Colts | 0 | 0 | Tyldesley Senior U18 Colts |
| Sunday, 27/02/2022 - Senior G Conference |
| Tyldesley Senior U18 Colts | Away Walkover | Blackburn Senior U18 Colts |
| Sunday, 06/03/2022 - Senior G Conference |
| Bury Senior U18 Colts | Liquidated Fixture | Tyldesley Senior U18 Colts |
| Sunday, 20/03/2022 - Lancashire Colts: Joe McDonough U18 Trophy |
| Tyldesley Senior U18 Colts | 20 | 20 | Manchester Senior U18 Colts |