| Saturday, 6 September 2025 |
| Bowdon 2nd XV | v | Wallasey |
| Crewe & Nantwich 2nd XV | v | Burnage 2nd XV |
| Firwood Waterloo 2nd XV | v | Ellesmere Port |
| Holmes Chapel | v | Broughton Park 2nd XV |
| Marple | v | Didsbury Toc H 2nd XV |
| Sandbach 3rd XV | v | Prenton |
| Saturday, 13 September 2025 |
| Broughton Park 2nd XV | v | Marple |
| Burnage 2nd XV | v | Wallasey |
| Didsbury Toc H 2nd XV | v | Sandbach 3rd XV |
| Ellesmere Port | v | Holmes Chapel |
| Firwood Waterloo 2nd XV | v | Bowdon 2nd XV |
| Saturday, 4 October 2025 |
| Bowdon 2nd XV | v | Burnage 2nd XV |
| Crewe & Nantwich 2nd XV | v | Didsbury Toc H 2nd XV |
| Holmes Chapel | v | Firwood Waterloo 2nd XV |
| Marple | v | Ellesmere Port |
| Sandbach 3rd XV | v | Broughton Park 2nd XV |
| Wallasey | v | Prenton |
| Saturday, 11 October 2025 |
| Broughton Park 2nd XV | v | Crewe & Nantwich 2nd XV |
| Didsbury Toc H 2nd XV | v | Wallasey |
| Ellesmere Port | v | Sandbach 3rd XV |
| Firwood Waterloo 2nd XV | v | Marple |
| Holmes Chapel | v | Bowdon 2nd XV |
| Prenton | v | Burnage 2nd XV |
| Saturday, 18 October 2025 |
| Bowdon 2nd XV | v | Prenton |
| Burnage 2nd XV | v | Didsbury Toc H 2nd XV |
| Crewe & Nantwich 2nd XV | v | Ellesmere Port |
| Marple | v | Holmes Chapel |
| Sandbach 3rd XV | v | Firwood Waterloo 2nd XV |
| Wallasey | v | Broughton Park 2nd XV |
| Saturday, 25 October 2025 |
| Prenton | v | Crewe & Nantwich 2nd XV |
| Saturday, 8 November 2025 |
| Broughton Park 2nd XV | v | Burnage 2nd XV |
| Didsbury Toc H 2nd XV | v | Prenton |
| Ellesmere Port | v | Wallasey |
| Firwood Waterloo 2nd XV | v | Crewe & Nantwich 2nd XV |
| Holmes Chapel | v | Sandbach 3rd XV |
| Marple | v | Bowdon 2nd XV |
| Saturday, 22 November 2025 |
| Bowdon 2nd XV | v | Didsbury Toc H 2nd XV |
| Burnage 2nd XV | v | Ellesmere Port |
| Crewe & Nantwich 2nd XV | v | Holmes Chapel |
| Prenton | v | Broughton Park 2nd XV |
| Sandbach 3rd XV | v | Marple |
| Wallasey | v | Firwood Waterloo 2nd XV |
| Saturday, 29 November 2025 |
| Broughton Park 2nd XV | v | Didsbury Toc H 2nd XV |
| Ellesmere Port | v | Prenton |
| Firwood Waterloo 2nd XV | v | Burnage 2nd XV |
| Holmes Chapel | v | Wallasey |
| Marple | v | Crewe & Nantwich 2nd XV |
| Sandbach 3rd XV | v | Bowdon 2nd XV |
| Saturday, 6 December 2025 |
| Bowdon 2nd XV | v | Broughton Park 2nd XV |
| Burnage 2nd XV | v | Holmes Chapel |
| Crewe & Nantwich 2nd XV | v | Sandbach 3rd XV |
| Didsbury Toc H 2nd XV | v | Ellesmere Port |
| Prenton | v | Firwood Waterloo 2nd XV |
| Wallasey | v | Marple |
| Saturday, 13 December 2025 |
| Crewe & Nantwich 2nd XV | v | Bowdon 2nd XV |
| Ellesmere Port | v | Broughton Park 2nd XV |
| Firwood Waterloo 2nd XV | v | Didsbury Toc H 2nd XV |
| Holmes Chapel | v | Prenton |
| Marple | v | Burnage 2nd XV |
| Sandbach 3rd XV | v | Wallasey |
| Saturday, 20 December 2025 |
| Bowdon 2nd XV | v | Ellesmere Port |
| Broughton Park 2nd XV | v | Firwood Waterloo 2nd XV |
| Burnage 2nd XV | v | Sandbach 3rd XV |
| Didsbury Toc H 2nd XV | v | Holmes Chapel |
| Prenton | v | Marple |
| Wallasey | v | Crewe & Nantwich 2nd XV |
| Saturday, 10 January 2026 |
| Bowdon 2nd XV | v | Firwood Waterloo 2nd XV |
| Crewe & Nantwich 2nd XV | v | Prenton |
| Holmes Chapel | v | Ellesmere Port |
| Marple | v | Broughton Park 2nd XV |
| Sandbach 3rd XV | v | Didsbury Toc H 2nd XV |
| Wallasey | v | Burnage 2nd XV |
| Saturday, 17 January 2026 |
| Broughton Park 2nd XV | v | Sandbach 3rd XV |
| Burnage 2nd XV | v | Bowdon 2nd XV |
| Didsbury Toc H 2nd XV | v | Crewe & Nantwich 2nd XV |
| Ellesmere Port | v | Marple |
| Firwood Waterloo 2nd XV | v | Holmes Chapel |
| Prenton | v | Wallasey |
| Saturday, 24 January 2026 |
| Bowdon 2nd XV | v | Holmes Chapel |
| Burnage 2nd XV | v | Prenton |
| Crewe & Nantwich 2nd XV | v | Broughton Park 2nd XV |
| Marple | v | Firwood Waterloo 2nd XV |
| Sandbach 3rd XV | v | Ellesmere Port |
| Wallasey | v | Didsbury Toc H 2nd XV |
| Saturday, 14 February 2026 |
| Broughton Park 2nd XV | v | Wallasey |
| Didsbury Toc H 2nd XV | v | Burnage 2nd XV |
| Ellesmere Port | v | Crewe & Nantwich 2nd XV |
| Firwood Waterloo 2nd XV | v | Sandbach 3rd XV |
| Holmes Chapel | v | Marple |
| Prenton | v | Bowdon 2nd XV |
| Saturday, 28 February 2026 |
| Bowdon 2nd XV | v | Marple |
| Burnage 2nd XV | v | Broughton Park 2nd XV |
| Crewe & Nantwich 2nd XV | v | Firwood Waterloo 2nd XV |
| Prenton | v | Didsbury Toc H 2nd XV |
| Sandbach 3rd XV | v | Holmes Chapel |
| Wallasey | v | Ellesmere Port |
| Saturday, 7 March 2026 |
| Broughton Park 2nd XV | v | Prenton |
| Didsbury Toc H 2nd XV | v | Bowdon 2nd XV |
| Ellesmere Port | v | Burnage 2nd XV |
| Firwood Waterloo 2nd XV | v | Wallasey |
| Holmes Chapel | v | Crewe & Nantwich 2nd XV |
| Marple | v | Sandbach 3rd XV |
| Saturday, 21 March 2026 |
| Bowdon 2nd XV | v | Sandbach 3rd XV |
| Burnage 2nd XV | v | Firwood Waterloo 2nd XV |
| Crewe & Nantwich 2nd XV | v | Marple |
| Didsbury Toc H 2nd XV | v | Broughton Park 2nd XV |
| Prenton | v | Ellesmere Port |
| Wallasey | v | Holmes Chapel |
| Saturday, 28 March 2026 |
| Broughton Park 2nd XV | v | Bowdon 2nd XV |
| Ellesmere Port | v | Didsbury Toc H 2nd XV |
| Firwood Waterloo 2nd XV | v | Prenton |
| Holmes Chapel | v | Burnage 2nd XV |
| Marple | v | Wallasey |
| Sandbach 3rd XV | v | Crewe & Nantwich 2nd XV |
| Saturday, 11 April 2026 |
| Bowdon 2nd XV | v | Crewe & Nantwich 2nd XV |
| Broughton Park 2nd XV | v | Ellesmere Port |
| Burnage 2nd XV | v | Marple |
| Didsbury Toc H 2nd XV | v | Firwood Waterloo 2nd XV |
| Prenton | v | Holmes Chapel |
| Wallasey | v | Sandbach 3rd XV |
| Saturday, 18 April 2026 |
| Crewe & Nantwich 2nd XV | v | Wallasey |
| Ellesmere Port | v | Bowdon 2nd XV |
| Firwood Waterloo 2nd XV | v | Broughton Park 2nd XV |
| Holmes Chapel | v | Didsbury Toc H 2nd XV |
| Marple | v | Prenton |
| Sandbach 3rd XV | v | Burnage 2nd XV |
| Saturday, 25 April 2026 |
| Broughton Park 2nd XV | v | Holmes Chapel |
| Burnage 2nd XV | v | Crewe & Nantwich 2nd XV |
| Didsbury Toc H 2nd XV | v | Marple |
| Ellesmere Port | v | Firwood Waterloo 2nd XV |
| Prenton | v | Sandbach 3rd XV |
| Wallasey | v | Bowdon 2nd XV |