| Round 1 |
| Saturday, 28 September 2019 |
| 1 | Manchester Hawks | v | Bye |
| 2 | Broughton Park 3rd XV | v | Bye |
| 3 | Rochdale 3rd XV | v | Bye |
| 4 | Broughton 2nd XV | v | Bye |
| 5 | Newcastle (Staffs) 3rd XV | Home Walkover | North Manchester 2nd XV |
| 6 | Bury 2nd XV | v | Bye |
| 7 | Aldwinians 4th XV | v | Bye |
| 8 | Trafford MV 3rd XV | v | Bye |
| 9 | Altrincham Kersal 3rd XV | v | Bye |
| 10 | Oldham 3rd XV | v | Bye |
| 12 | Aldwinians 3rd XV | v | Bye |
| 13 | Preston Grasshoppers 5th XV | v | Bye |
| 14 | Kirkby Lonsdale RUFC Wanderers | v | Bye |
| 15 | Bury 3rd XV | v | Bye |
| 16 | Orrell St James | v | Bye |
| 17 | Colne & Nelson 2nd XV | v | Bye |
| 18 | Burnley 2nd XV | v | Bye |
| 19 | Aspull 3rd XV | v | Bye |
| 21 | Southport 3rd XV | v | Bye |
| 22 | Bolton 3rd XV | v | Bye |
| 23 | Linley & Kidsgrove 2nd XV | v | Bye |
| 24 | Helsby 2nd XV | v | Bye |
| 26 | Merseyside Police | v | Bye |
| 27 | Moore 2nd XV | v | Bye |
| 28 | Port Sunlight 2nd XV | 20 | 19 | Oxton Parkonians 2nd XV |
| 29 | Wirral 4th XV | v | Bye |
| 30 | Birkenhead Park 4th XV | 45 | 19 | Winnington Park 3rd XV |
| 31 | Oldershaw 2nd XV | v | Bye |
| 32 | Anselmians 3rd XV | v | Bye |
| Saturday, 26 October 2019 |
| 11 | Orrell 3rd XV | Home Walkover | Fleetwood 3rd XV |
| 25 | Mossley Hill 2nd XV | 24 | 27 | Prenton 2nd XV |
| Saturday, 9 November 2019 |
| 20 | Garstang Blues (2nd XV) | 36 | 12 | Sedgley Park 4th XV |
| Round 2 |
| Saturday, 26 October 2019 |
| Manchester Hawks | Away Walkover | Broughton Park 3rd XV |
| Rochdale 3rd XV | 56 | 7 | Broughton 2nd XV |
| Preston Grasshoppers 5th XV | 0 | 40 | Kirkby Lonsdale RUFC Wanderers |
| Bury 3rd XV | Home Walkover | Orrell St James |
| Linley & Kidsgrove 2nd XV | Home Walkover | Helsby 2nd XV |
| Moore 2nd XV | Home Walkover | Port Sunlight 2nd XV |
| Saturday, 2 November 2019 |
| Prenton 2nd XV | Home Walkover | Merseyside Police |
| Saturday, 9 November 2019 |
| Newcastle (Staffs) 3rd XV | 14 | 36 | Bury 2nd XV |
| Aldwinians 4th XV | Away Walkover | Trafford MV 3rd XV |
| Altrincham Kersal 3rd XV | 36 | 5 | Oldham 3rd XV |
| Southport 3rd XV | 24 | 17 | Bolton 3rd XV |
| Saturday, 21 December 2019 |
| Orrell 3rd XV | Home Walkover | Aldwinians 3rd XV |
| Colne & Nelson 2nd XV | 5 | 17 | Burnley 2nd XV |
| Wirral 4th XV | 21 | 37 | Birkenhead Park 4th XV |
| Saturday, 4 January 2020 |
| Aspull 3rd XV | 0 | 48 | Garstang Blues (2nd XV) |
| Oldershaw 2nd XV | Home Walkover | Anselmians 3rd XV |
| Round 3 |
| Saturday, 14 December 2019 |
| Kirkby Lonsdale RUFC Wanderers | 33 | 14 | Bury 3rd XV |
| Saturday, 25 January 2020 |
| Broughton Park 3rd XV | Home Walkover | Rochdale 3rd XV |
| Bury 2nd XV | 33 | 12 | Trafford MV 3rd XV |
| Altrincham Kersal 3rd XV | 22 | 29 | Orrell 3rd XV |
| Burnley 2nd XV | 13 | 54 | Garstang Blues (2nd XV) |
| Southport 3rd XV | Home Walkover | Linley & Kidsgrove 2nd XV |
| Prenton 2nd XV | 14 | 28 | Moore 2nd XV |
| Birkenhead Park 4th XV | 29 | 5 | Oldershaw 2nd XV |
| Round 4 |
| Saturday, 22 February 2020 |
| Southport 3rd XV | 28 | 0 | Moore 2nd XV |
| Saturday, 29 February 2020 |
| Bury 2nd XV | 27 | 21 | Orrell 3rd XV |
| Kirkby Lonsdale RUFC Wanderers | 21 | 19 | Broughton Park 3rd XV |
| Saturday, 21 March 2020 |
| Birkenhead Park 4th XV | v | Garstang Blues (2nd XV) |
| Round 5 |
| Saturday, 4 April 2020 |
| Kirkby Lonsdale RUFC Wanderers | v | Southport 3rd XV |
| TBC | v | Bury 2nd XV |
| Round 6 |
| Saturday, 2 May 2020 |
| TBC | v | TBC |